Abdominal aortic aneurysm (AAA) is on the 10th position of the causes of death in men above 55 years of age. Method of treatment of AAA measuring above 5,5 cm is the classical surgery or endovascular procedure. Death and complication rates associated with surgery are still high. For this reason further studies on pathogenesis, pathophysiology and treatment of abdominal aortic aneurysm are needed. Numerous animal models of AAA have been developed. Research is conducted on predisposed animals and on models, in which AAA have been induced by chemical or physical methods. Swine are good experimental model for the improvement of new surgical techniques. Many physical protocols are used to produce aneurysm in swine (especially operational), combinations of physical and chemical methods are also introduced and constantly improved.

Bones are metabolically active tissues, which undergo a lifelong process of modeling. Bone metabolism is controlled by system factors as well as by local ones, besides balanced diet plays a significant role. Polyunsaturated fatty acids (PUFA) raise an interest as natural substances that can affect bone cells and modify their metabolism. They are the precursors of eicosanoids which are involved in a number of regulatory mechanisms, among others, at the level of bone tissue. With the participation of COX there appear prostaglandins, prostacyclins and monoenes thromboxanes, while under the influence of LOX leukotrienes. From arachidonic acid (AA) under the influence of COX is formed PGE , which in turn mediates in the impact on calciotropic hormones bone tissue, proresorptive cytokines and growth factors. Adequate supplementation reduces the activity of AA resulting in a diminution of PGE level, thereby weakening the intensity of atrophic changes in bone tissue. In the light of conducted research on the treatment and in particular on the prevention, PUFA diet supplementation plays a significant role in the metabolism of both animal and human bone tissue.

The study presented concerned an influence of an application of fish oil from cod liver with marine microalgae in feed doses of dairy cows in the first period of lactation on selected biochemical parameters of blood and milk yield. The fish oil with microalgae was applied to cows from 7^th day of lactation for a period of 8 weeks, in an amount of 1% of feed dose dry matter. The additives used caused decrease in feed intake, what in turn resulted in lowered milk yield. Also a reduction of fat and protein content in milk was observed. Increased PUFA content in feed dose caused an increase in triglycerides, cholesterol and β-hydroxybutyrate acid content in blood serum. An increase in total bilirubin concentration was also noted, however enzymes activity did not point any functional liver disorders.